ISDA: 9S8J

Deposition Date 2025-08-05

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9S8J

Keywords:

TRANSFERASE

Title:

Structure of protein kinase CK2alpha mutant R191Q associated with the Okur-Chung Neurodevelopmental Syndrome

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.48 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 43 21 2

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Casein kinase II subunit alph
Mutagens:R191Q
Chain IDs:A, B
Chain Length:411
Number of Molecules:2
Biological Source:Homo sapiens

Ligand Molecules

ANP

SO4

Primary Citation

Investigation of the structure-dysfunction relationship of various OCNDS-related CK2alpha mutants

Werner, C, Gast, A, Caefer, D, Fellhoefer, J, Meyer, S.C, Jordan, S, Buchwald, L.M, Than, T.L, Schwartz, D, Jose, J, Niefind, K.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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