ISDA: 9S7U

Deposition Date 2025-08-05

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9S7U

Keywords:

HYDROLASE

Title:

X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive mutant, in complex with an inhibitor Ac-gamma-Glu-Dap(thiooxalyl)-OH

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Drosophila melanogaster

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.54 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

I 2 2 2

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Glutamate carboxypeptidase 2
Chain IDs:A
Chain Length:707
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

A1JML

EDO

NAG

PEG

Primary Citation

X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive mutant, in complex with an inhibitor Ac-gamma-Glu-Dap(thiooxalyl)-OH

Novakova, Z, Schenkmayerova, A, Motlova, L, Barinka, C.Show

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Primary Citation of related structures

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