ISDA: 9S77

Deposition Date 2025-08-04

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

9S77

Keywords:

TRANSFERASE

Title:

Structure of protein kinase CK2alpha mutant S51R associated with the Okur-Chung Neurodevelopmental Syndrome

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.79 Å

R-Value Free:

0.20

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 42 21 2

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Casein kinase II subunit alph
Mutagens:S51R
Chain IDs:A
Chain Length:411
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

NIO

SO4

Primary Citation

Biophysical and structural characterization of mutants of CK2alpha related to the Okur-Chung neurodevelopmental syndrome

Werner, C, Gast, A, Caefer, D, Meyer, S.C, Buchwald, L.M, Than, T.L, Harasimowicz, H, Jose, J, Schwartz, D, Niefind, K.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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