9S3J image
Deposition Date 2025-07-24
Release Date 2026-07-01
Last Version Date 2026-07-01
Entry Detail
PDB ID:
9S3J
Keywords:
SIGNALING PROTEIN
Title:
Crystal structure of the human tumor necrosis factor receptor 1 extracellular domain in complex with a picolinic acid based ligand at 1.77A resolution
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.77 Å
R-Value Free:
0.25
R-Value Work:
0.22
R-Value Observed:
0.22
Space Group:
P 41 21 2
9S3J validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tumor necrosis factor recepto
Gene (Uniprot):TNFRSF1A
Chain IDs:A, B
Chain Length:164
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P19438 Pfam ID:PF00020
Ligand Molecules
A1JLJ
PO4
Primary Citation
Discovery of ligands for the TNFR1 extracellular domain using fragment-based drug discovery
To Be Published ? ? ? (?)
Primary Citation of related structures
9S3J
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