ISDA: 9RVP

Deposition Date 2025-07-08

Release Date 2025-07-30

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9RVP

Keywords:

RNA

Title:

Protein 2A from Theiler's murine encephalomyelitis virus (TMEV) bound to RNA pseudoknot

Biological Source:

Source Organism(s):

Theiler's encephalomyelitis virus (Taxon ID: 12124)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.22

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

C 1 2 1

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Genome polyprotein
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Theiler's encephalomyelitis virus

UniProt ID:Q88595,B4YYP2

Polymer Type:polyribonucleotide
Molecule:RNA pseudoknot
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Theiler's encephalomyelitis virus

Primary Citation

A protein-dependent riboswitch activates ribosomal frameshifting in cardioviruses.

Betts, J.K, Jeffries, C.M, Passchier, T.C, Kung, H.C.Y, Graham, S.P, Abdelhamid, M.A.S, Howard, J.A.L, Craggs, T.D, Graham, S.C, Brierley, I, Leake, M.C, Quinn, S.D, Hill, C.H.Show

Mol.Cell 86 3545 ? (2026)

PMID: 42628533 DOI: 10.1016/j.molcel.2026.07.036

Primary Citation of related structures

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