9RVK image
Deposition Date 2025-07-08
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9RVK
Keywords:
TRANSFERASE
Title:
Crystal structure of Aurora-A bound to DBL5
Biological Source:
Source Organism(s):
synthetic construct (Taxon ID: 32630)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.79 Å
R-Value Free:
0.23
R-Value Work:
0.19
Space Group:
P 21 21 21
9RVK validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:DBL5
Chain IDs:A
Chain Length:65
Number of Molecules:1
Biological Source:synthetic construct
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Aurora kinase A
Gene (Uniprot):AURKA
Chain IDs:B
Chain Length:282
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O14965 Pfam ID:PF00069 EC:2.7.11.1
Ligand Molecules
ADP
CL
GOL
MPD
Primary Citation
Selective miniprotein inhibitors of Aurora-A kinase designed using interaction-motif scaffolding
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.07.12.737516
Primary Citation of related structures
9RVK
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