9RTD image
Deposition Date 2025-07-02
Release Date 2026-07-15
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9RTD
Keywords:
OXIDOREDUCTASE
Title:
Crystal structure of DNA aptamer C8N5t in complex with Plasmodium falciparum lactate dehydrogenase
Biological Source:
Source Organism(s):
Plasmodium falciparum (Taxon ID: 5833)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.10 Å
R-Value Free:
0.26
R-Value Work:
0.20
Space Group:
P 21 21 21
9RTD validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:L-lactate dehydrogenase
Chain IDs:A, B, C, D
Chain Length:329
Number of Molecules:4
Biological Source:Plasmodium falciparum
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (32-MER)
Chain IDs:E (auth: G)
Chain Length:40
Number of Molecules:1
Biological Source:synthetic construct
Primary Citation
Selection and validation of novel DNA aptamer panel co-specific to Plasmodium falciparum and Plasmodium ovale lactate dehydrogenase.
Mol Ther Nucleic Acids 37 102977 102977 (2026)
PMID: 42381705 DOI: 10.1016/j.omtn.2026.102977
Primary Citation of related structures
9RTD
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