9RNJ image
Deposition Date 2025-06-19
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
9RNJ
Keywords:
MEMBRANE PROTEIN
Title:
Cryo-EM structure of the human potassium chloride cotransporter T906A/T1007A phospho-knockout mutants KCC2b bound ATP in LMNG (outward-facing state, dimer)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.86 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9RNJ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Isoform 2 of Solute carrier f
Gene (Uniprot):SLC12A5
Chain IDs:A (auth: B), B (auth: A)
Chain Length:1166
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9H2X9 Pfam ID:PF00324, PF03522
Ligand Molecules
ATP
CL
JUX
NA
Primary Citation
Distinct cytoplasmic domain interactions control autoinhibition of the neuronal potassium coupled chloride transporter KCC2
To Be Published ? ? ? (?)
Primary Citation of related structures
9RNJ
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