9RKI image
Deposition Date 2025-06-13
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9RKI
Keywords:
MEMBRANE PROTEIN
Title:
Mixed model refinement of beta-2 Adrenergic receptor with photoazolol in dark state and Light state, 17 nanoseconds after light activation, recorded at LCLS
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Tequatrovirus T4 (Taxon ID: 10665)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.60 Å
R-Value Free:
0.23
R-Value Work:
0.19
Space Group:
C 1 2 1
9RKI validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Beta-2 adrenergic receptor,En
Gene (Uniprot):E, ADRB2
Chain IDs:A
Chain Length:442
Number of Molecules:1
Biological Source:Homo sapiens, Tequatrovirus T4
UniProt ID:P07550,P00720 Pfam ID:PF00001, PF00959 EC:3.2.1.17
Ligand Molecules
12P
1PE
A1JHU
ACM
CLR
EDO
GOL
OLC
PLM
SO4
Primary Citation
Structural Mechanism of an Efficacy Photoswitch Targeting the beta 2 -adrenergic Receptor.
Angew.Chem.Int.Ed.Engl. ? e17995 e17995 (2026)
PMID: 41848496 DOI: 10.1002/anie.202517995
Primary Citation of related structures
9RKI
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