ISDA: 9RGE

Deposition Date 2025-06-06

Release Date 2026-06-17

Last Version Date 2026-06-17

Entry Detail

PDB ID:

9RGE

Keywords:

MEMBRANE PROTEIN

Title:

CryoEM structure of human alpha1beta3gamma2 GABA(A)R in complex with GARLH4 and the Neuroligin2 transmembrane helix, in CL47a

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.10 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Gene (Uniprot):GABRA1
Chain IDs:A, D
Chain Length:405
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P14867 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Gene (Uniprot):GABRB3
Chain IDs:B, E
Chain Length:439
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P28472 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Gene (Uniprot):GABRG2
Chain IDs:C
Chain Length:411
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P18507 Pfam ID:PF02931, PF02932

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Neuroligin-2
Gene (Uniprot):NLGN2
Chain IDs:F (auth: H)
Chain Length:29
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NFZ4

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:LHFPL tetraspan subfamily mem
Gene (Uniprot):LHFPL4
Chain IDs:G (auth: L)
Chain Length:185
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q7Z7J7 Pfam ID:PF10242

Ligand Molecules