9RCY image
Deposition Date 2025-05-30
Release Date 2026-04-29
Last Version Date 2026-04-29
Entry Detail
PDB ID:
9RCY
Keywords:
TRANSFERASE
Title:
Structure of protein kinase CK2alpha mutant R21Q associated with the Okur-Chung Neurodevelopmental Syndrome
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.35 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.21
Space Group:
P 43 21 2
9RCY validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Casein kinase II subunit alph
Gene (Uniprot):CSNK2A1
Mutagens:R21Q
Chain IDs:A, B
Chain Length:411
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P68400 EC:2.7.11.1
Ligand Molecules
SO4
Primary Citation
Functional characterization of 42 CK2 alpha de novo variants associated with Okur-Chung neurodevelopmental syndrome.
Febs J. ? ? ? (2026)
PMID: 41978434 DOI: 10.1111/febs.70538
Primary Citation of related structures
9RCY
Feedback Form
Name
Email
Institute
Feedback