ISDA: 9R98

Deposition Date 2025-05-19

Release Date 2026-01-21

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9R98

Keywords:

HYDROLASE

Title:

DhhP of Borrelia burgdorferi in complex with AMP (SAD/Fe)

Biological Source:

Source Organism(s):

Borreliella burgdorferi (Taxon ID: 139)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.30 Å

R-Value Free:

0.20

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DHH family
Gene (Uniprot):BB_0619
Chain IDs:A, B, C, D, E, F, G, H
Chain Length:325
Number of Molecules:8
Biological Source:Borreliella burgdorferi

UniProt ID:O51564 Pfam ID:PF01368, PF02272 EC:3.1.4.59

Ligand Molecules

AMP

Primary Citation

Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center.

Klima, M, Dejmek, M, Palusova, A, Chalupska, D, Pachl, P, Huskova, A, Hranicek, J, Chalupsky, K, Moos, M, Nencka, R, Perner, J, Boura, E.Show

Structure ? ? ? (2026)

PMID: 41742401 DOI: 10.1016/j.str.2026.01.016

Primary Citation of related structures

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