ISDA: 9R44

Deposition Date 2025-05-07

Release Date 2026-05-20

Last Version Date 2026-05-20

Entry Detail

PDB ID:

9R44

Keywords:

APOPTOSIS

Title:

Crystal structure of human caspase-9 CARD

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.46 Å

R-Value Free:

0.26

R-Value Work:

0.20

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Caspase-9
Gene (Uniprot):CASP9
Chain IDs:A, B (auth: E), C (auth: H), D (auth: L)
Chain Length:101
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P55211 Pfam ID:PF00619 EC:3.4.22.62

Ligand Molecules

SO4

Primary Citation

Mechanistic insights into the caspase-9 CARD oligomerization.

Rawal, S, Bohn, S, Pavkov-Keller, T, Desfosses, A, Madl, T, Alderson, T.R.Show

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Primary Citation of related structures

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