9R2I image
Deposition Date 2025-04-30
Release Date 2026-03-25
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9R2I
Keywords:
CYTOSOLIC PROTEIN
Title:
Cryo-EM structure of the complex CDK16:CCNY:14-3-3
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9R2I validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein eta
Gene (Uniprot):YWHAH
Chain IDs:A, B
Chain Length:248
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q04917
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyclin-dependent kinase 16
Gene (Uniprot):CDK16
Chain IDs:C
Chain Length:395
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q00536 EC:2.7.11.22
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyclin-Y
Gene (Uniprot):CCNY
Chain IDs:D
Chain Length:346
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8ND76
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SEP D SER modified residue
Ligand Molecules
AGS
MG
Primary Citation
Structural basis of the cyclin Y/14-3-3 protein-mediated activation of CDK16.
Nat Commun ? ? ? (2026)
PMID: 41857027 DOI: 10.1038/s41467-026-70778-5
Primary Citation of related structures
9R2I
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