9R1T image
Deposition Date 2025-04-28
Release Date 2026-05-27
Last Version Date 2026-05-27
Entry Detail
PDB ID:
9R1T
Keywords:
MEMBRANE PROTEIN
Title:
Structure of the human chimera HCN112 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP.
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.34 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9R1T validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Potassium/sodium hyperpolariz
Gene (Uniprot):HCN1, Hcn2
Chain IDs:A, B, C, D
Chain Length:658
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:O60741,O88703 Pfam ID:PF08412, PF00520, PF00027
Ligand Molecules
CMP
Primary Citation
Interactions between CNBD and HCND domains control gating inhibition in HCN1 family.
To Be Published ? ? ? (?)
Primary Citation of related structures
9R1U
9R1V
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