ISDA: 9QZH

Deposition Date 2025-04-23

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9QZH

Keywords:

LIGASE

Title:

GID4 in complex with Compound 33

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.19 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glucose-induced degradation p
Gene (Uniprot):GID4
Chain IDs:A, B, C, D
Chain Length:166
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q8IVV7 Pfam ID:PF09783

Ligand Molecules

A1JCD

Primary Citation

Novel chemical probes and conformational flexibility of GID4 - a substrate receptor of the Human CTLH E3 ligase complex

Pastok, M.W, Gorecka-Minakowska, K.M, Klejnot, M, Skowron, A.N, Wisniewski, J, Walczak, M.J.Show

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