ISDA: 9QYK

Deposition Date 2025-04-18

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9QYK

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of human L-lactate Dehydrogenase B protein in complex with NADH, oxamate and sertraline

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.06 Å

R-Value Free:

0.21

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:L-lactate dehydrogenase B cha
Gene (Uniprot):LDHB
Chain IDs:A, B, C, D
Chain Length:348
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P07195 EC:1.1.1.27

Ligand Molecules

NAI

OXM

SRE

Primary Citation

Crystal structure of human L-lactate Dehydrogenase B protein in complex with NADH, oxamate and sertraline

Van Gysel, M, Wouters, J.Show

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