ISDA: 9QW9

Deposition Date 2025-04-14

Release Date 2026-04-29

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9QW9

Keywords:

CYTOSOLIC PROTEIN

Title:

Human vault protein - primed conformation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Komagataella phaffii

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.09 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Major vault protein
Gene (Uniprot):MVP
Chain IDs:A, B (auth: AA), C (auth: AB), D (auth: AC), E (auth: B), F (auth: BA), G (auth: BB), H (auth: C), I (auth: CA), J (auth: CB), K (auth: D), L (auth: DA), M (auth: DB), N (auth: E), O (auth: EA), P (auth: EB), Q (auth: F), R (auth: FA), S (auth: FB), T (auth: G), U (auth: GA), V (auth: GB), W (auth: H), X (auth: HA), Y (auth: HB), Z (auth: I), AA (auth: IA), BA (auth: IB), CA (auth: J), DA (auth: JA), EA (auth: JB), FA (auth: K), GA (auth: KA), HA (auth: KB), IA (auth: L), JA (auth: LA), KA (auth: LB), LA (auth: M), MA, NA (auth: MB), OA (auth: N), PA (auth: NA), QA (auth: NB), RA (auth: O), SA (auth: OA), TA (auth: OB), UA (auth: P), VA (auth: PA), WA (auth: PB), XA (auth: Q), YA (auth: QA), ZA (auth: QB), AB (auth: R), BB (auth: RA), CB (auth: RB), DB (auth: S), EB (auth: SA), FB (auth: SB), GB (auth: T), HB (auth: TA), IB (auth: TB), JB (auth: UA), KB (auth: UB), LB (auth: V), MB (auth: VA), NB (auth: VB), OB (auth: W), PB (auth: WA), QB (auth: WB), RB (auth: X), SB (auth: XA), TB (auth: XB), UB (auth: Y), VB (auth: YA), WB (auth: YB), XB (auth: Z), YB (auth: ZA), ZB
Chain Length:893
Number of Molecules:78
Biological Source:Homo sapiens

UniProt ID:Q14764

Ligand Molecules

Primary Citation

Structural flexibility of the human vault protein revealed by high-resolution cryo-EM and molecular dynamics simulations

Lapenta, F, Palacio-Rodriguez, K, Cruz Leon, S, Marrancone, S, Aupic, J, Marechal, N, Durand, A, Moussaoui, D, Covaceuszach, S, Gangupam, B, d Ercole, C, Parra, C, Cotugno, D, Tomaino, G, Tortora, P, de Marco, A, Cassetta, A, Magistrato, A, Hummer, G.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form