ISDA: 9QVZ

Deposition Date 2025-04-13

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9QVZ

Keywords:

TRANSFERASE

Title:

Adhiron-mediated Identification of a Novel and Selective Allosteric Pocket in Aurora Kinase A

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.39 Å

R-Value Free:

0.33

R-Value Work:

0.29

R-Value Observed:

0.29

Space Group:

P 32 2 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Aurora kinase A
Gene (Uniprot):AURKA
Mutagens:C290A, C393A
Chain IDs:A
Chain Length:285
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O14965 Pfam ID:PF00069 EC:2.7.11.1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Adhiron (JR-Adh1)
Chain IDs:B
Chain Length:100
Number of Molecules:1
Biological Source:synthetic construct

UniProt ID:9QVZ

Ligand Molecules