ISDA: 9QUH

Deposition Date 2025-04-10

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9QUH

Keywords:

HYDROLASE

Title:

Structure of human MTH1 in complex with 8DG by MicroED using high electron fluence

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON CRYSTALLOGRAPHY

Resolution:

2.32 Å

R-Value Free:

0.26

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:7,8-dihydro-8-oxoguanine trip
Gene (Uniprot):NUDT1
Chain IDs:A, B
Chain Length:159
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P36639 Pfam ID:PF00293 EC:3.6.1.55

Ligand Molecules

8DG

SO4

Primary Citation

Continuous Serial Electron Diffraction for High Quality Protein Structures

Hofer, G, Wang, L, Pacoste, L, Hager, P, Fonjallaz, A, Williams, L, Worrall, J, Steiner, R, Xu, H, Zou, X.Show

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