ISDA: 9QRV

Deposition Date 2025-04-04

Release Date 2026-02-11

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9QRV

Keywords:

BLOOD CLOTTING

Title:

Crystal Structure of an anti-VWF CK Domain Fab in Complex with the C-Terminal CK Domain of Cynomolgus Monkey von Willebrand Factor.

Biological Source:

Source Organism(s):

Macaca fascicularis (Taxon ID: 9541)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Cricetulus griseus

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.50 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:von Willebrand factor
Gene (Uniprot):VWF
Chain IDs:A (auth: D)
Chain Length:113
Number of Molecules:1
Biological Source:Macaca fascicularis

UniProt ID:A0A2K5X4G5

Polymer Type:polypeptide(L)
Molecule:VH-CH1
Chain IDs:B (auth: H)
Chain Length:224
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Kappa light chain
Chain IDs:C (auth: L)
Chain Length:213
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules