9QRC image
Deposition Date 2025-04-03
Release Date 2026-04-15
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9QRC
Keywords:
VIRAL PROTEIN
Title:
SARS-CoV-2 nsp14 with 6-methyl-2-[(4-methylphenyl)methyl]pyridazin-3-one
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.40 Å
R-Value Free:
0.23
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 21 21 21
9QRC validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine-N7 methyltransferase
Gene (Uniprot):rep
Chain IDs:A
Chain Length:523
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1 Pfam ID:PF06471 EC:2.7.7.48
Ligand Molecules
A1I9I
DMS
PO4
ZN
Primary Citation
Fragment-based screening reveals novel SARS-CoV-2 nsp14 targeting fragments.
To be published ? ? ? (?)
Primary Citation of related structures
9QRC
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