ISDA: 9QQE

Deposition Date 2025-03-31

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9QQE

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of the SN230G6 Fab - HLA-A*02:01 human alloantibody-HLA complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.78 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Chain IDs:A
Chain Length:275
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Chain IDs:C (auth: B)
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:SN230G6 Fab Heavy Chain
Chain IDs:D (auth: H)
Chain Length:238
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:SN230G6 Fab Light Chain
Chain IDs:E (auth: L)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Peptide VLHDDLLEA
Chain IDs:B (auth: P)
Chain Length:9
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Cryo-EM structure of the SN230G6 Fab - HLA-A*02:01 human alloantibody-HLA complex

Zampieri, V, Priddey, A, Schneider, S, Heidt, S, Kosmoliaptsis, V, Marquez, J.A.Show

To be published ? ? ? (?)

Primary Citation of related structures

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