ISDA: 9QIZ

Deposition Date 2025-03-18

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9QIZ

Keywords:

HYDROLASE

Title:

Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase from P. aeruginosa: F324A Mutant Complexed with Adenosine and Rubidium Ions Replacing Native Potassium

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa PAO1 (Taxon ID: 208964)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.06 Å

R-Value Free:

0.22

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Adenosylhomocysteinase
Gene (Uniprot):ahcY
Chain IDs:A, B, C, D
Chain Length:472
Number of Molecules:4
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:Q9I685 Pfam ID:PF05221, PF00670 EC:3.3.1.1

Ligand Molecules

ADN

NAD

PO4

Primary Citation

Crystal structure of the S-adenosyl-L-homocysteine hydrolase from P. aeruginosa, a Q65N mutant probed with rubidium to prove disruption of a potassium binding site.

Malecki, P.H, Wozniak, K, Stepniewska, M, Brzezinski, K.Show

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