ISDA: 9QHN

Deposition Date 2025-03-16

Release Date 2026-02-11

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9QHN

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of mouse TRPM3 alpha 2 in APO state

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transient receptor potential
Gene (Uniprot):Trpm3
Chain IDs:A, B, C, D
Chain Length:1177
Number of Molecules:4
Biological Source:Mus musculus

UniProt ID:J9SQF3 Pfam ID:PF18139, PF25508, PF00520, PF16519

Ligand Molecules

3PH

CLR

Primary Citation

Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3.

Bazeli, B, Shkumatov, A.V, Schenck, S, Vanherck, J.C, Janssens, A, Spieser, S.A.H, Marchand, D, Roelens, R, Chaltin, P, Marchand, A, Vriens, J, Voets, T, Brunner, J.D.Show

Nat Commun 17 ? ? (2026)

PMID: 41922314 DOI: 10.1038/s41467-026-71226-0

Primary Citation of related structures

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