ISDA: 9QHA

Deposition Date 2025-03-14

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9QHA

Keywords:

SUGAR BINDING PROTEIN

Title:

Crystal structure of human dendritic cell immunoreceptor (DCIR) extracellular domain in complex with galactose-terminated biantennary complex-type N-glycan

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.25

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 65

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:C-type lectin domain family 4
Gene (Uniprot):CLEC4A
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9UMR7 Pfam ID:PF00059

Ligand Molecules

Primary Citation

The human and mouse dendritic cell receptor DCIR binds to LRP1 N-glycans containing terminal galactoses, including the alpha-Gal antigen

Raymond, B.B.A, Sneperger, T, Rousset, S, Gilles, N, Bally, A, Stella, A, Hipgrave Ederveen, A.L, Marcoux, J, Trimaglio, G, Thepaut, T, Lagarrigue, F, Burlet-Schiltz, O, Wuhrer, M, Fieschi, F, Demange, P, Neyrolles, O, Rombouts, Y.Show

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Primary Citation of related structures

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