ISDA: 9QG4

Deposition Date 2025-03-13

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9QG4

Keywords:

TRANSCRIPTION

Title:

Human PPAR-gamma ligand binding domain in complex with LW130

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.23

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Peroxisome proliferator-activ
Gene (Uniprot):PPARG
Chain IDs:A (auth: B), B (auth: A)
Chain Length:275
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P37231 Pfam ID:PF00104

Ligand Molecules

A1I6O

Primary Citation

Development and characterization of novel indazole-based PPAR-gamma partial agonists

Koops, A.A, Oerlemans, G.J.M, Brunsveld, L.Show

To be published ? ? ? (?)

Primary Citation of related structures

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