ISDA: 9QEB

Deposition Date 2025-03-08

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

9QEB

Keywords:

TRANSCRIPTION

Title:

CryoEM structure of transcribing RNA polymerase II elongation complex

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)

Expression System(s):

Saccharomyces cerevisiae

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.26 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPO21
Chain IDs:A
Chain Length:1733
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P04050 Pfam ID:PF04997, PF00623, PF04983, PF05000, PF04998, PF04992, PF04990, PF05001 EC:2.7.7.6

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB2
Chain IDs:B
Chain Length:1224
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P08518 Pfam ID:PF04563, PF04561, PF04565, PF04566, PF04567, PF00562, PF04560 EC:2.7.7.6

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB3
Chain IDs:C
Chain Length:318
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P16370 Pfam ID:PF01193, PF01000

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB4
Chain IDs:D
Chain Length:221
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20433 Pfam ID:PF03874

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB5
Chain IDs:E
Chain Length:215
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20434 Pfam ID:PF03871, PF01191

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPO26
Chain IDs:F
Chain Length:155
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20435 Pfam ID:PF01192

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB7
Chain IDs:G
Chain Length:171
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P34087 Pfam ID:PF03876, PF00575

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB8
Chain IDs:H
Chain Length:146
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P20436 Pfam ID:PF03870

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB9
Chain IDs:I
Chain Length:122
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P27999 Pfam ID:PF02150, PF01096

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB10
Chain IDs:J
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P22139 Pfam ID:PF01194

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB11
Chain IDs:K
Chain Length:120
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P38902 Pfam ID:PF13656

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPC10
Chain IDs:L
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

UniProt ID:P40422 Pfam ID:PF03604

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (44-MER)
Chain IDs:M (auth: N)
Chain Length:44
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*AP*UP*CP*GP*AP*GP
Chain IDs:N (auth: R)
Chain Length:9
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (44-MER)
Chain IDs:O (auth: T)
Chain Length:44
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae

Ligand Molecules

ATP

Primary Citation

CryoEM structure of transcribing RNA polymerase II

Li, Q, Yi, G, Zhang, P, Wang, D.Show

To Be Published ? ? ? (?)

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