ISDA: 9QDO

Deposition Date 2025-03-06

Release Date 2026-03-18

Last Version Date 2026-10-14

Entry Detail

PDB ID:

9QDO

Keywords:

DE NOVO PROTEIN

Title:

Crystal structure of the aromatic oligoamide foldamer binder Nanofitin C10 fused to a coiled-coil domain

Biological Source:

Source Organism(s):

Sulfolobus acidocaldarius (Taxon ID: 2285)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.40 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 21 21 21

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nanofitin C10-coiled-coil
Chain IDs:A, B
Chain Length:100
Number of Molecules:2
Biological Source:Sulfolobus acidocaldarius

Primary Citation

A protein-foldamer supramolecular synthon for self-assembled hybrid architectures.

Sigl, J, Morozov, V, Wang, L, Sachs, J, Merlet, E, Largy, E, Geue, N, Osterlund, N, Kwon, S, Sanchez, F, Candela, L, Huet, S, Pagel, K, Ferrand, Y, Douat, C, Mackereth, C.D, Huc, I.Show

Nat.Chem. 18 1819 1827 (2026)

PMID: 42608459 DOI: 10.1038/s41557-026-02222-6

Primary Citation of related structures

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