ISDA: 9QC6

Deposition Date 2025-03-04

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9QC6

Keywords:

TRANSLATION

Title:

Structure of eIF2B decamer bound to (P)eIF2 alpha and Compound A-(S)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.83 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B1
Chain IDs:A, B
Chain Length:326
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q14232 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B2
Chain IDs:C, D
Chain Length:351
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P49770 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B3
Chain IDs:E, F
Chain Length:452
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9NR50 Pfam ID:PF00483, PF25084

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B4
Chain IDs:G, H
Chain Length:523
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9UI10 Pfam ID:PF01008

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):EIF2B5
Chain IDs:I, J
Chain Length:742
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q13144 Pfam ID:PF02020

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Gene (Uniprot):EIF2S1
Chain IDs:K
Chain Length:210
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P05198 Pfam ID:PF00575, PF07541 EC:3.6.5.3

Modified Residue