9Q3S image
Deposition Date 2025-08-19
Release Date 2026-05-27
Last Version Date 2026-05-27
Entry Detail
PDB ID:
9Q3S
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Cryo-EM structure of PGT121 Fab and Rhesus macaque Ab4 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
Biological Source:
Source Organism(s):
Human immunodeficiency virus 1 (Taxon ID: 11676)
Macaca mulatta (Taxon ID: 9544)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9Q3S validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP.664 gp41
Gene (Uniprot):env
Chain IDs:A (auth: B), G (auth: C), M (auth: J)
Chain Length:153
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:Q2N0S5
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:BG505 SOSIP.664 gp120
Gene (Uniprot):env
Chain IDs:B (auth: G), H (auth: A), N (auth: I)
Chain Length:481
Number of Molecules:3
Biological Source:Human immunodeficiency virus 1
UniProt ID:Q2N0S5
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ab 4 Fab heavy chain
Chain IDs:C (auth: H), I (auth: D), O (auth: K)
Chain Length:229
Number of Molecules:3
Biological Source:Macaca mulatta
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ab 4 Fab light chain
Chain IDs:D (auth: L), J (auth: E), P (auth: M)
Chain Length:215
Number of Molecules:3
Biological Source:Macaca mulatta
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:PGT121 Fab heavy chain
Chain IDs:E (auth: h), K (auth: d), Q (auth: k)
Chain Length:229
Number of Molecules:3
Biological Source:Homo sapiens
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:PGT121 Fab light chain
Chain IDs:F (auth: l), L (auth: e), R (auth: m)
Chain Length:215
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
NAG
Primary Citation
Cryo-EM structure of PGT121 Fab and Rhesus macaque Ab4 Fab in complex with HIV-1 Env trimer BG505 SOSIP.664
To Be Published ? ? ? (?)
Primary Citation of related structures
9Q3S
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