ISDA: 9Q3E

Deposition Date 2025-08-18

Release Date 2026-07-08

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9Q3E

Keywords:

VIRAL PROTEIN

Title:

Cryo-EM structure of RotavirusA NSP1-ELOB-ELOC-CUL3

Biological Source:

Source Organism(s):

Rotavirus A (Taxon ID: 28875)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Elongin-B
Chain IDs:B
Chain Length:118
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Elongin-C
Chain IDs:C
Chain Length:112
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Cullin-3
Chain IDs:D (auth: L)
Chain Length:771
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Non-structural protein 1
Chain IDs:A (auth: N)
Chain Length:486
Number of Molecules:1
Biological Source:Rotavirus A

Ligand Molecules

Primary Citation

Virome-wide ubiquitin ligase discovery reveals diverse mechanisms of immune evasion.

Glassman, C.R, Baek, K, Hou, G, Zeng, Q, Nardone, C, Juergens, K.B, Fujimura, E, O'Leary, C.N, Li, M.Z, Paulo, J.A, Fischer, E.S, Ding, S, Harper, J.W, Elledge, S.J.Show

Science ? ? ? (2026)

PMID: 42424437 DOI: 10.1126/science.aec6299

Primary Citation of related structures

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