ISDA: 9Q0F

Deposition Date 2025-08-12

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9Q0F

Keywords:

SIGNALING PROTEIN

Title:

Structure of angiotensin II type 1 receptor bound to a b-arrestin biased allosteric modulator stabilized by a synthetic nanobody

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Homo sapiens, Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.02 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Type-1 angiotensin II recepto
Chain IDs:A
Chain Length:366
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:TRV023
Chain IDs:B
Chain Length:8
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Nanobody NB.AT110i1
Chain IDs:C (auth: D)
Chain Length:134
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules