ISDA: 9Q07

Deposition Date 2025-08-12

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9Q07

Keywords:

TRANSPORT PROTEIN

Title:

Structure-based design of a nutrient acquisition protein enhances neutralizing antibodies and protection for the development of a gonococcal vaccine

Biological Source:

Source Organism(s):

Neisseria gonorrhoeae MS11 (Taxon ID: 528354)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.60 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

C 1 2 1

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Crystal structure of N-lobe o
Mutagens:K218A, K219A, E220A, E236A, K237A, K238A
Chain IDs:A, B, C, D
Chain Length:679
Number of Molecules:4
Biological Source:Neisseria gonorrhoeae MS11

Primary Citation

Structure-based engineering of a nutrient acquisition protein enhances neutralizing antibodies and protection for the development of a gonococcal vaccine.

Au, N.Y.T, Zhong, E.Z.L, Fegan, J.E, Islam, E.A, Xu, S.X, Ng, D, Shah, M, Caruso, L.L, Lai, C.C.L, Schryvers, A.B, Gray-Owen, S.D, Moraes, T.F.Show

Biorxiv ? ? ? (2025)

PMID: 41279537 DOI: 10.1101/2025.11.06.685839

Primary Citation of related structures

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