ISDA: 9PZZ

Deposition Date 2025-08-12

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9PZZ

Keywords:

PROTEIN BINDING

Title:

Genetically encoded fluorescent nanobody H11 with 4-(7-nitro-2,1,3-benzoxadiazolyl)-alanine (NBDO) at the W37 position complexed with Arc-NL

Biological Source:

Source Organism(s):

Vicugna pacos (Taxon ID: 30538)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.56 Å

R-Value Free:

0.22

R-Value Work:

0.18

Space Group:

C 1 2 1

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Fluorescent nanobody H11
Mutagens:W37Z
Chain IDs:A, C
Chain Length:135
Number of Molecules:2
Biological Source:Vicugna pacos

Polymer Type:polypeptide(L)
Molecule:Activity-regulated cytoskelet
Chain IDs:B, D
Chain Length:75
Number of Molecules:2
Biological Source:Homo sapiens

Primary Citation

Site-Specific FLIM Probes via Genetic Encoding of Environmentally Responsive Benzodiazoles

Qianzhu, H, Habel, E, Butler, S.M, Abdelkader, E.H, Paul, N, Zhou, X, Otting, G, Joliffe, K.A, Huber, T.Show

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