9PZC image
Deposition Date 2025-08-09
Release Date 2026-07-01
Last Version Date 2026-07-01
Entry Detail
PDB ID:
9PZC
Keywords:
VIRAL PROTEIN
Title:
HCMV trimer in complex with G1L (II), G1L (A), B5L, C4K, B1K, A7K, A12K, and C5K Fabs
Biological Source:
Source Organism(s):
Human betaherpesvirus 5 (Taxon ID: 10359)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9PZC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Envelope glycoprotein H
Gene (Uniprot):UL75
Chain IDs:A
Chain Length:743
Number of Molecules:1
Biological Source:Human betaherpesvirus 5
UniProt ID:Q69155
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Envelope glycoprotein L
Gene (Uniprot):UL115
Chain IDs:B
Chain Length:268
Number of Molecules:1
Biological Source:Human betaherpesvirus 5
UniProt ID:Q8JP80
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin lambda variabl
Gene (Uniprot):IGLV1-51
Chain IDs:C
Chain Length:110
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01701 Pfam ID:PF07686
Protein Blast
Polymer Type:polypeptide(L)
Molecule:G1L Fab heavy chain
Chain IDs:D
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin heavy variable
Gene (Uniprot):IGHV1-46
Chain IDs:E
Chain Length:119
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01743 Pfam ID:PF07686
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin kappa variable
Gene (Uniprot):IGKV3-20
Chain IDs:F
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01619 Pfam ID:PF07686
Protein Blast
Polymer Type:polypeptide(L)
Molecule:A12K Fab heavy chain
Chain IDs:G
Chain Length:116
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin heavy variable
Gene (Uniprot):IGHV4-34
Chain IDs:H
Chain Length:123
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P06331 Pfam ID:PF07686
Protein Blast
Polymer Type:polypeptide(L)
Molecule:A12K Fab light chain
Chain IDs:I
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin kappa variable
Gene (Uniprot):IGKV1-39
Chain IDs:J
Chain Length:107
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01597 Pfam ID:PF07686
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin heavy variable
Gene (Uniprot):IGHV4-39
Chain IDs:K
Chain Length:121
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01824 Pfam ID:PF07686
Protein Blast
Polymer Type:polypeptide(L)
Molecule:B5L Fab light chain
Chain IDs:L
Chain Length:110
Number of Molecules:1
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:C5K Fab light chain
Chain IDs:M
Chain Length:106
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Immunoglobulin heavy variable
Gene (Uniprot):IGHV1-46
Chain IDs:N
Chain Length:123
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P01743 Pfam ID:PF07686
Protein Blast
Polymer Type:polypeptide(L)
Molecule:C4K Fab heavy chain
Chain IDs:O
Chain Length:119
Number of Molecules:1
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:C4K Fab light chain
Chain IDs:P
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
NAG
Primary Citation
Structural characterization of antibodies for synergistic HCMV neutralization
To Be Published ? ? ? (?)
Primary Citation of related structures
9PZC
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