9PVY image
Deposition Date 2025-08-04
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9PVY
Keywords:
PROTEIN FIBRIL
Title:
Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I L90P amyloidosis patient
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.15 Å
Aggregation State:
FILAMENT
Reconstruction Method:
HELICAL
9PVY validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Apolipoprotein A-I
Gene (Uniprot):APOA1
Chain IDs:A, B, C, D, E, F, G, H, I, J
Chain Length:243
Number of Molecules:10
Biological Source:Homo sapiens
UniProt ID:P02647 Pfam ID:PF01442
Ligand Molecules
NA
Primary Citation
Structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations, revealed by cryo-EM
To Be Published ? ? ? (?)
Primary Citation of related structures
9PVY
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