ISDA: 9PVG

Deposition Date 2025-08-01

Release Date 2026-01-28

Last Version Date 2026-01-28

Entry Detail

PDB ID:

9PVG

Keywords:

SIGNALING PROTEIN

Title:

Co-crystal structure of two CCM2 PTB domains bound to a KRIT1 peptide encompassing NPxF2 and NPxF3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.00 Å

R-Value Free:

0.29

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Malcavernin
Gene (Uniprot):CCM2
Chain IDs:A, B, C, F (auth: D)
Chain Length:180
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q9BSQ5

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Krev interaction trapped prot
Gene (Uniprot):KRIT1
Chain IDs:D (auth: E), E (auth: F)
Chain Length:29
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O00522

Ligand Molecules

Primary Citation

Co-crystal structure of two CCM2 PTB domains bound to a KRIT1 peptide encompassing NPxF2 and NPxF3

Fisher, O.S, Boggon, T.J.Show

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Primary Citation of related structures

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