9PRW image
Deposition Date 2025-07-24
Release Date 2025-12-31
Last Version Date 2025-12-31
Entry Detail
PDB ID:
9PRW
Keywords:
TRANSFERASE
Title:
Cryo-EM structure of human DNMT3A/3L
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.66 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9PRW validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA (cytosine-5)-methyltransf
Gene (Uniprot):DNMT3A
Chain IDs:A, D
Chain Length:633
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9Y6K1 Pfam ID:PF00855, PF17980, PF21255, PF00145 EC:2.1.1.37
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA (cytosine-5)-methyltransf
Gene (Uniprot):DNMT3L
Chain IDs:B, C
Chain Length:386
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9UJW3 Pfam ID:PF17980, PF21255
Ligand Molecules
SAH
ZN
Primary Citation
Cryo-EM structure of human DNMT3A2/3L
To be published ? ? ? (?)
Primary Citation of related structures
9PRW
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