ISDA: 9PRT

Deposition Date 2025-07-24

Release Date 2026-07-01

Last Version Date 2026-07-01

Entry Detail

PDB ID:

9PRT

Keywords:

HYDROLASE

Title:

Human 19S proteasome bound to TXNL1 PITH domain but with low density for RPT1, RPT2, and RPN1

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.02 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPT6
Gene (Uniprot):PSMC5
Chain IDs:A (auth: C)
Chain Length:310
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62195 Pfam ID:PF16450, PF00004, PF17862

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPT3
Gene (Uniprot):PSMC4
Chain IDs:B (auth: D)
Chain Length:350
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P43686 Pfam ID:PF16450, PF00004, PF17862

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPT4
Gene (Uniprot):PSMC6
Chain IDs:C (auth: E)
Chain Length:70
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62333 Pfam ID:PF16450, PF00004, PF17862

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPT5
Gene (Uniprot):PSMC3
Chain IDs:D (auth: F)
Chain Length:439
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P17980 Pfam ID:PF16450, PF00004, PF17862

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN2
Gene (Uniprot):PSMD1
Chain IDs:E (auth: U)
Chain Length:953
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q99460 Pfam ID:PF21505, PF01851, PF13646, PF18004 EC:5.6.1.5

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN3
Gene (Uniprot):PSMD3
Chain IDs:F (auth: V)
Chain Length:534
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O43242 Pfam ID:PF25573, PF01399, PF08375

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN5
Gene (Uniprot):PSMD12
Chain IDs:G (auth: W)
Chain Length:456
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O00232 Pfam ID:PF22241, PF01399, PF18098

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN6
Gene (Uniprot):PSMD11
Chain IDs:H (auth: X)
Chain Length:422
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O00231 Pfam ID:PF18055, PF01399, PF18503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN7
Gene (Uniprot):PSMD6
Chain IDs:I (auth: Y)
Chain Length:389
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q15008 Pfam ID:PF10602, PF01399, PF21154

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN8
Gene (Uniprot):PSMD7
Chain IDs:J (auth: Z)
Chain Length:324
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P51665 Pfam ID:PF01398, PF13012

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN9
Gene (Uniprot):PSMD13
Chain IDs:K (auth: a)
Chain Length:376
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9UNM6 Pfam ID:PF22037, PF01399

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN10
Gene (Uniprot):PSMD4
Chain IDs:L (auth: b)
Chain Length:377
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P55036 Pfam ID:PF13519, PF02809

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN11
Gene (Uniprot):PSMD14
Chain IDs:M (auth: c)
Chain Length:310
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O00487 Pfam ID:PF01398, PF23594 EC:3.4.19.-

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RPN12
Gene (Uniprot):PSMD8
Chain IDs:N (auth: d)
Chain Length:350
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P48556 Pfam ID:PF10075

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DSS1
Gene (Uniprot):SEM1
Chain IDs:O (auth: e)
Chain Length:70
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P60896 Pfam ID:PF05160

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:TXNL1
Gene (Uniprot):TXNL1
Chain IDs:P (auth: g)
Chain Length:289
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O43396 Pfam ID:PF00085, PF06201

Ligand Molecules