ISDA: 9PR3

Deposition Date 2025-07-23

Release Date 2026-02-04

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9PR3

Keywords:

VIRAL PROTEIN

Title:

Cryo-EM structure of stabilized H5N1 A/Texas/37/2024 hemagglutinin fused to foldon

Biological Source:

Source Organism(s):

Influenza A virus (Taxon ID: 11320)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin, foldon fusion
Chain IDs:A, B, C
Chain Length:555
Number of Molecules:3
Biological Source:Influenza A virus

Ligand Molecules

NAG

Primary Citation

Stabilization of the H5 clade 2.3.4.4b hemagglutinin improves vaccine-elicited neutralizing antibody responses in mice.

Dosey, A, Dadonaite, B, Gillespie, R.A, Leaf, E.M, Vukovich, M.J, McGowan, J, Grey, E, Muramatsu, H, Jun, R.H.J, Pardi, N, Kanekiyo, M, Bloom, J.D, King, N.P.Show

Sci Transl Med 18 eaea8770 eaea8770 (2026)

PMID: 41779867 DOI: 10.1126/scitranslmed.aea8770

Primary Citation of related structures

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