ISDA: 9PN7

Deposition Date 2025-07-19

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9PN7

Keywords:

HYDROLASE

Title:

Crystal structure of human mitochondrial ClpP protease C144R mutant

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.02 Å

R-Value Free:

0.25

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:ATP-dependent Clp protease pr
Gene (Uniprot):CLPP
Mutagens:C144R
Chain IDs:A, B, C, D (auth: E), E (auth: F), F (auth: G), G (auth: D)
Chain Length:221
Number of Molecules:7
Biological Source:Homo sapiens

UniProt ID:Q16740 Pfam ID:PF00574 EC:3.4.21.92

Primary Citation

A molecular basis for Perrault syndrome type 3 and the identification of novel substrates of the mitochondrial ClpXP protease

Houry, W.A, Mabanglo, M.F.Show

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