ISDA: 9PLP

Deposition Date 2025-07-15

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9PLP

Keywords:

APOPTOSIS/IMMUNE SYSTEM

Title:

Crystal structure of netrin-1 in complex with anti-netrin-1 Fab (NP137 Fab)

Biological Source:

Source Organism(s):

Gallus gallus (Taxon ID: 9031)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

4.99 Å

R-Value Free:

0.32

R-Value Work:

0.28

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Netrin-1
Gene (Uniprot):NTN1
Chain IDs:A, B
Chain Length:443
Number of Molecules:2
Biological Source:Gallus gallus

UniProt ID:Q90922 Pfam ID:PF00055, PF24973, PF00053

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:NP137 Fab heavy chain
Chain IDs:C, E (auth: H)
Chain Length:222
Number of Molecules:2
Biological Source:Mus musculus

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:NP137 Fab light chain
Chain IDs:D, F (auth: L)
Chain Length:225
Number of Molecules:2
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Crystal structure of netrin-1 in complex with anti-netrin-1 Fab (NP137 Fab)

Rafiei, F, Bailey-Elkin, B.A, Stetefeld, J.Show

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Primary Citation of related structures

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