9PKU image
Deposition Date 2025-07-14
Release Date 2026-01-07
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9PKU
Keywords:
Title:
Crystal Structure of YEATS domain of human YEATS2 in complex with LS-131 peptide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
Resolution:
2.88 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.21
Space Group:
C 1 2 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:YEATS domain-containing prote
Gene (Uniprot):YEATS2
Chain IDs:A, C
Chain Length:135
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:LS-131 peptide
Chain IDs:B, D
Chain Length:5
Number of Molecules:2
Biological Source:Homo sapiens
Primary Citation
Complex-specific inhibitors for interrogating ATAC histone acetyltransferase complex.
Nat.Chem.Biol. 22 471 481 (2026)
PMID: 41513852 DOI: 10.1038/s41589-025-02132-7
Primary Citation of related structures
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