ISDA: 9PH8

Deposition Date 2025-07-08

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9PH8

Keywords:

TRANSFERASE

Title:

Crystal structure of SARS-CoV-2 nsp14 with SAM bound

Biological Source:

Source Organism(s):

Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.79 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine-N7 methyltransferase
Gene (Uniprot):rep
Chain IDs:A, B
Chain Length:531
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

UniProt ID:P0DTD1 Pfam ID:PF06471 EC:2.7.7.48

Ligand Molecules

SAM

Primary Citation

Predictive deep learning and active learning identifies compounds targeting SARS-CoV-2 non-structural protein nsp14

Guan, D.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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