ISDA: 9PGH

Deposition Date 2025-07-07

Release Date 2026-02-25

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9PGH

Keywords:

TRANSCRIPTION/DNA

Title:

The cryo-EM structure of C. crescentus RNAP-Sigma73-CCNA_03891/CCNA_01149 promoter complex

Biological Source:

Source Organism(s):

Caulobacter vibrioides NA1000 (Taxon ID: 565050)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.54 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Chain IDs:A, B
Chain Length:338
Number of Molecules:2
Biological Source:Caulobacter vibrioides NA1000

UniProt ID:Q9A8S9

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Chain IDs:C
Chain Length:1356
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

UniProt ID:Q9AAU2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Chain IDs:D
Chain Length:1396
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

UniProt ID:Q9AAU1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase s
Chain IDs:E
Chain Length:119
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

UniProt ID:P58066

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RNA polymerase sigma factor R
Chain IDs:F
Chain Length:652
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

UniProt ID:P52324

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (55-MER)-non template
Chain IDs:G (auth: H)
Chain Length:99
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (43-MER)-template
Chain IDs:H (auth: I)
Chain Length:99
Number of Molecules:1
Biological Source:Caulobacter vibrioides NA1000

Ligand Molecules

Primary Citation

Transcription activation mechanism of a noncanonical DNA damage response pathway by the WYL-activator, DriD.

Singh, R.R, Chinni, A, Cannistraci, E, Salinas, R, Yadav, S, Gozzi, K, Schumacher, M.A.Show

Sci Adv 12 eaec6337 eaec6337 (2026)

PMID: 41861017 DOI: 10.1126/sciadv.aec6337

Primary Citation of related structures

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