ISDA: 9PFE

Deposition Date 2025-07-04

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

9PFE

Keywords:

STRUCTURAL PROTEIN

Title:

NMR structure of slow skeletal Myosin Binding Protein-C M-domain tri-helix bundle

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

200

Conformers Submitted:

Selection Criteria:

structures with the least restraint violations

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform 4 of Myosin-binding p
Gene (Uniprot):MYBPC1
Chain IDs:A
Chain Length:45
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q00872 Pfam ID:PF18362

Ligand Molecules

Primary Citation

From bedside to bench: A multimodal approach uncovering the molecular basis of the MYBPC1-linked Myotrem myopathy

Iyer, A, Wright, N.T, Cook, M.E, Takagi, Y, Johnson, B.A, Biancalana, V, Massier, M, Spodenkiewicz, M, Poirsier, C, Vallecillo, B, Boyer, F.C, Pineau, C, Hensley, L, Sellers, J.R, Varney, K.M, Weber, D.J, Kontrigianni-Konstantopoulos, A.Show

Proc.Natl.Acad.Sci.USA ? ? ? (2026)

Primary Citation of related structures

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