ISDA: 9PB0

Deposition Date 2025-06-25

Release Date 2026-07-29

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9PB0

Keywords:

TOXIN

Title:

Solution NMR structure of conotoxin AoIA - globular disulfide isomer

Biological Source:

Source Organism(s):

Conus araneosus (Taxon ID: 101286)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

Conformers Submitted:

Selection Criteria:

Molprobity score

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Chi-conotoxin-like Ar1311
Chain IDs:A
Chain Length:11
Number of Molecules:1
Biological Source:Conus araneosus

UniProt ID:P0CI23

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
HYP	A	PRO	modified residue

Ligand Molecules

Primary Citation

Structural and functional basis of antinociceptive action of chi-conotoxin AoIA at the noradrenaline transporter

Belleza, O.J.V, Zhang, H, Schmidhammer, H, Gonzalez, T.I, Ciotu, C.I, Tomasevic, N, Ocampo, C.M.M, Fernando, J.C, Koehbach, J, Schwarz, P, Al Makhlouf, M, Tajti, G, Hasinger, S, Kastner, N, Avsar, O, Retzl, B, Jantsch, K, Jiang, Y, Hellinger, R, Fischer, M.J.M, Rosengren, K.J, Gruber, C.W, Villaraza, A.J.L, Stockner, T, Spetea, M, Xu, H.E, Sitte, H.H.Show

Nat.Struct.Mol.Biol. ? ? ? (2026)

DOI: 10.1038/s41594-026-01838-z

Primary Citation of related structures

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