ISDA: 9PAM

Deposition Date 2025-06-25

Release Date 2026-07-01

Last Version Date 2026-07-01

Entry Detail

PDB ID:

9PAM

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of HCoV-OC43 3CLpro with ALG-097655 (Inhibitor 2)

Biological Source:

Source Organism(s):

Human coronavirus OC43 (Taxon ID: 31631)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.31 Å

R-Value Free:

0.26

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

I 2 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:3C-like proteinase
Gene (Uniprot):Pp1ab
Chain IDs:A, B
Chain Length:302
Number of Molecules:2
Biological Source:Human coronavirus OC43

UniProt ID:U3M7V4

Ligand Molecules

A1CHJ

Primary Citation

Crystal structure of HCoV-OC43 3CLpro with ALG-097655 (Inhibitor 2)

Reddem, E.R, Forouhad, F, Shapiro, L, Stoycheva, A.Show

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Primary Citation of related structures

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