ISDA: 9P1R

Deposition Date 2025-06-10

Release Date 2026-06-17

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9P1R

Keywords:

FLAVOPROTEIN

Title:

Crystal structure of TCZ9 from Streptomyces

Biological Source:

Source Organism(s):

Streptomyces sp. AJS327 (Taxon ID: 2545265)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.56 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 61 2 2

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:FAD-binding oxidoreductase
Chain IDs:A
Chain Length:477
Number of Molecules:1
Biological Source:Streptomyces sp. AJS327

Ligand Molecules

FAD

Primary Citation

Structural and biochemical basis for cannabinoid cyclase activity in marine bacterial flavoenzymes.

Love, A.C, Sirohi, H, Hubert, F.M, Kao, Y.C, Quinnell, D.E, Lan, T, Gappy, R, Sheehy, M, Hsu, J, Lee, A, Zangwill, L, Chang, T, Palfey, B.A, Chang, G, Moore, B.S.Show

Nat.Chem.Biol. ? ? ? (2026)

PMID: 42414636 DOI: 10.1038/s41589-026-02257-3

Primary Citation of related structures

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